Clinical efficacy, safety and tolerability of BIO-C (micronized silymarin) as a galactagogue
(PubMed) Ding W, Zhou DL, Jiang X, Lu LS
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Compared to the liver, we observed that the kidney has: (1) similar increased use of energy-related metabolites and production of urea cycle and ammonia-related intermediates, suggesting a shared catabolism in AKI, and (2) higher pools of energy metabolism intermediates in AKI
Phase 2 and mechanistic studies report reduced hunger perception, delayed gastric emptying, and effects on postprandial glucoregulatory hormones consistent with amylin signalling, though exact glucagon findings should be attributed to the original trial reports [2]